I was able to figure out how to subscribe in Paho-MQTT multiple Topics, I am pretty sure I can have it inspect for stuff coming in from a independent units and even Zigbee via Home Assistant.
So it may be possible to have 1 monitored script to watch all this.
Just to confirm, I was able to view Home Assistant submitted mqtt messages over multiple topics.
So I may be able to do more.
Getting cool.
Another confirm, yesterday I got my fitbit steps in.
Weight: 342.8